P-type ca 2+ transporter
SERCA is a P-type ATPase. It resides in the sarcoplasmic reticulum (SR) within myocytes. It is a Ca ATPase that transfers Ca from the cytosol of the cell to the lumen of the SR. This uses energy from ATP hydrolysis during muscle relaxation. There are 3 major domains on the cytoplasmic face of SERCA: the phosphorylation and nucleotide-binding domains, which form the catalytic site, and the actuator domain, which is involved in the t… WebApr 1, 2004 · The SR Ca 2+-ATPase has become the archetype of the P-type-ATPase family, because its atomic structure is the only one so far to have been determined …
P-type ca 2+ transporter
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WebApr 11, 2024 · Summary. Predicted to enable P-type calcium transporter activity. Involved in several processes, including calcium ion transport from cytosol to endoplasmic reticulum; … WebDietary source • Of the major minerals, magnesium ranks sixth (Ca 2+ > P > K + > Na + > Cl-> Mg 2+) in overall abundance in the body. • More than half of the body’s magnesium is in the bones. Much of the rest is in the muscles and soft tissues. • Magnesium is found in a wide variety of foods.: Nuts, seeds, and whole-grain cereals (especially oats and barley): Food …
WebIt is a member of the platelet-derived growth factor (PDGF) family, and characterized by a cysteine-knot structure and disulfide-linked homodimer. Alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) have been identified in humans, with 120, 164 and 188 aa isoforms found in mouse. VEGF binds the type I transmembrane ...
WebJul 30, 2014 · The members of P-type ATPases family transport metal ions including Cd 2+, and thus play important role an ion homeostasis. The present study elucidates the role of P-type 2B Ca 2+ ATPase (OsACA6) in Cd 2+ stress tolerance. The transcript levels of OsACA6 were up-regulated upon Cd 2+, Zn 2+ and Mn 2+ exposure. WebMar 10, 2024 · Enables P-type calcium transporter activity; P-type manganese transporter activity; and calcium ion binding activity. Involved in cellular metal ion homeostasis; macroautophagy; and metal ion transport. Located in Golgi membrane. Used to study Hailey-Hailey disease. Human ortholog(s) of this gene implicated in Hailey-Hailey disease. …
WebNov 8, 2024 · The transport cycle of a typical P-type ATPase is initiated by binding of Mg 2+ –ATP and the transported substrate ion to an inward-facing E1 state, followed by …
WebApr 1, 2004 · Type IIA comprises the SR Ca 2+-ATPase (for recent reviews, see Refs 25,26), whereas plasma-membrane Ca 2+-pumps belong to type IIB. The SR Ca 2+-ATPase has become the archetype of the P-type ... shower extender bathtubWebP-type ATPases are a large family of membrane proteins that perform active ion transport across biological membranes. In these proteins, the energy-providing ATP hydrolysis is coupled to ion transport of one or two ion species across the respective membrane. The pump function of the investigated pumps is described by a so-called Post-Albers cycle. shower extender for filter and handheldWebDec 29, 2024 · Calcium (Ca 2+ ), a universal second messenger, is involved in many aspects of plant development and responses to the environment. Abiotic and biotic stresses such as cold, heat, and salt, as well as pathogen infection, act on Ca 2+ -permeable channels to cause transient increases in cytosolic free Ca 2+ concentration ( [Ca 2+] cyt ). shower extenders on amazonWebApr 29, 2024 · A characteristic feature of P-ATPases is their ability to transport the substrate cations against a strong electrochemical potential, including a concentration gradient ( … shower extender hoseWebP2 transport. The P2 transport was a United States Maritime Commission design for a passenger ship which could be readily converted into a troop transport. Three variants of the design were built, the P2-SE2-R1 ( Admirals ), P2-S2 … shower extender pipeWebFeb 19, 2024 · In plant cells, three major classes of transporters control Ca 2+ homeostasis, namely channels, exchangers, and pumps (i.e. ATPases). These Ca 2+ -ATPases are … shower extender rodWebJan 18, 2000 · P-type ATPases form a large family of cation-transporting pumps. These ubiquitous membrane proteins have been classified into five groups according to substrate specificity ().The best-characterized group transports the ions of hard Lewis acids and can be further subdivided into monovalent ion pumps for ions such as K +, Na +, and H +, and … shower extension home depot