Web8 apr. 2024 · Munshi et al. recently showed some high-risk patients’ characteristics, like high-risk cytogenetic, ISS stage, number of prior lines of therapy and penta-drug refractoriness, as predictive of the achievement of sustained MRD negativity at 6 and 12 months, which correlate with better outcomes. WebLeptomeningeal myelomatosis in previously treated high-risk kappa light chain multiple myeloma: case report and literature review Maro Ohanian1, James Alaly2, Stephen Samuel3, Christian Cable1, Kathleen Halka11Department of Hematology/Oncology, 2Department of Radiology, 3Department of Hematopathology, Scott and White …
Updated Diagnostic Criteria and Staging System for Multiple …
WebThe International Myeloma Working Group consensus updates the definition for high-risk (HR) multiple myeloma based on cytogenetics Several cytogenetic abnormalities such as t (4; 14), del (17/17p), t (14; 16), t (14; 20), nonhyperdiploidy, and gain (1q) were identified that confer poor prognosis. Web4 apr. 2024 · Major progress in the treatment of multiple myeloma has been made in the last several years. However, myeloma remains incurable and patients with high-risk cytogenetics or advanced stage disease have an even worsen survival. Only allogeneic transplantation may have curative potential in some patients. cruise port address in barcelona spain
The importance of cytogenetic and molecular aberrations in …
Web1 jan. 2024 · Early responders after 2 cycles of treatment had higher rates of light chain disease, anemia, renal failure, International Staging System (ISS) stage III disease, and high-risk cytogenetics ... Web19 mei 2016 · The Revised International Staging System has been developed for myeloma that incorportates high-risk cytogenetic abnormalities. Multiple myeloma evolves from … Web8 apr. 2024 · This review will focus on the main points regarding risk stratification, treatment and monitoring of MM, highlighting the most recent evidence that could modify the management of this still incurable disease. Multiple Myeloma (MM) remains a difficult to treat disease mainly due to its biological heterogeneity, of which we are more and more … build tf urf