WebApr 7, 2024 · Embryonic Meniscus Smooth Muscle Cells are the Precursors of Fibrochondrocyte Progenitors of the Mature Meniscus Our previous study identified … WebMay 1, 2024 · Here, we study the fibrochondrogenic differentiation of human tendon-derived stem/progenitor cells (TSPCs) both in vitro and in vivo. Methods TSPCs were isolated from human patellar tendon tissues and investigated for their multidifferentiation potential.
Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells …
WebFeb 21, 2024 · Chondrocytes, which make up the majority of the cells in all samples, are further split into three empirically defined populations: cartilage progenitor cells (CPCs), … WebSupporting: 2, Mentioning: 48 - Reconstruction of the anisotropic structure and proper function of the knee meniscus remains an important challenge to overcome, because the complexity of the zonal tissue organization in the meniscus has important roles in load bearing and shock absorption. Current tissue engineering solutions for meniscus … thai bremerton
Single-cell RNA-seq analysis identifies meniscus …
WebPseudotime analysis showed endothelial cells and fibrochondrocyte progenitors (FCP) existed at the pseudospace trajectory start. Melanoma cell adhesion molecule ( (MCAM)/CD146) was highly expressed in two clusters. CD146+ meniscus cells differentiated into osteoblasts and adipocytes and formed colonies. WebAdditional studies with adult progenitors, both bone marrow and adipose derived, also show positive and even synergistic results in combining a TGF-β growth factor with a BMP [23–25,45]. The increases in GAG and collagen seen in this study may have been due to direct effects of the BMPs, BMP-induced increases in TGF-β receptors [ 24 ], or a ... WebRegulatory Mechanisms in the Chondrogenesis of Mesenchymal Progenitors: The Roles of Cyclic Tensile Loading and Cell-Matrix Interactions. View/ Open. connelly_john_t_200708_phd.pdf (9.828Mb) Date 2007-06-14. Author. Connelly, John Thomas. Metadata Show full item record. symplicity psrp