WebThe agrin cleavage process influences agrin function in normal physiology as well as pathology, as NMJ maturation is dependent upon normal agrin cleavage and aberrant agrin cleavage is linked to neurological disease such as mental retardation and neuromuscular pathologies such as muscular dystrophy and sarcopenia (Bentzinger et al., 2005; Reif et … WebOct 29, 2014 · C-terminal agrin fragment (CAF, size 22 kDa) is a promising new biomarker for kidney function. This study evaluated the usefulness of CAF as a serum biomarker for residual renal function (RRF) in patients undergoing automated peritoneal dialysis (APD). Patients and methods
Evaluation of C‐terminal Agrin Fragment as a marker of muscle wasting
WebC-terminal agrin fragment (tCAF) is a promising biomarker for glomerular filtration. Data regarding biomarkers that have the ability to predict rapid progression of chronic kidney … WebMay 16, 2024 · Recently, the relevance of circulating C-terminal agrin fragment (CAF) as an accessible screening method alternative for sarcopenia has gained credence. Accordingly, this study aimed to verify the pertinence of plasma CAF as a biomarker for sarcopenia. Three hundred healthy adults aged between 50 and 83 years took part in … fly to rankin inlet
Evaluation of C-terminal Agrin Fragment as a marker of muscle wasting ...
WebJan 7, 2024 · Accordingly, we explored whether genes encoding agrin ( AGRN) and neurotrypsin ( PRSS12) were associated with sarcopenia phenotypes: muscle mass, strength and plasma C-terminal agrin fragment (CAF). PhenoScanner was used to determine if AGRN and/or PRSS12 variants had previously been implicated with … WebJan 1, 2013 · The C-terminal Agrin Fragment caused by degeneration of the neuromuscular junction can be measured in human serum. CAF appears to be a … WebJul 5, 2016 · The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule Arezoo Daryadel, … green power investor relations